A role for the Fas antigen in lupus?
نویسنده
چکیده
منابع مشابه
Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses.
Fas-mediated apoptosis is an important contributor to contraction of Ag-driven T cell responses acting only on activated Ag-specific T cells. The effects of targeted Fas deletion on selected cell populations are well described however little is known regarding the consequences of Fas deletion on only activated Ag-specific T cells. We addressed this question using the parent-into-F(1) (P-->F(1))...
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عنوان ژورنال:
- Postgraduate medical journal
دوره 72 843 شماره
صفحات -
تاریخ انتشار 1996